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The American College of Radiologys TI-RADS assigns points to thyroid nodules based on five features: Composition (how cystic a thyroid looks) Echogenicity (the ability to bounce back an echo during an ultrasound exam) Shape (wider-than-tall, or taller-than-wide) Margin (how far the thyroid extends around surrounding organs) Echogenic focus (bright spots or shadows seen on an ultrasound) Based on that ratings scale, nodules are then classified as: Benign (non-cancerous) Not suspicious Mildly, moderately, or highly suspicious 5

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The SM1 voxel was centered on the right central sulcus, posterior to the hand-knob(Yousry et al., 1997) in the axial plane and rotated to align with the cortical surface(Puts et al., 2011)

HBV-HDV superinfected patients were defined as new HDV diagnoses over 90 days from the first date of CHBV diagnosis