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RAW264.7 cells were repeatedly disrupted using a dounce homogenizer with a tight-fitting pestle

Selective and membrane-permeable small molecule inhibitors of nicotinamide N-methyltransferase reverse high fat diet-induced obesity in mice

Because individuals with the GSTM1 null genotype have been reported to have higher levels of polycyclic aromatic hydrocarbon-dGMP adducts (which can induce genetic mutations) in lung tissue than those with the GSTM1 genotype [4], such genetic variants have been extensively studied as candidates for lung cancer susceptibility, but studies have yielded apparently conflicting results [6142]

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In such cases, systemic therapy is the only viable option