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The primary mechanical injury in TBI triggers secondary injury cascades involving neuroinflammation, oxidative stress, mitochondrial dysfunction, and excitotoxicity

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Young Scientists & NIH Funding 02:39:38 Grant Funding, Identity & Race

Dysbiosis of gut microbiota, altered bile acid metabolism, 14 and disruption of the gut-liver barrier 15 further exacerbate MASLD progression

For example, when oxygen molecules break into single atoms with unpaired electrons, they become unstable free radicals eager to bind with other atoms or molecules