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Studies have suggested that abnormalities in this polarity switch, caused by altered levels of NKCC1 and KCC2, may underlie the pathogenesis of various neurological disorders, including ASD ( GABAB receptors are G-protein coupled receptors (GPCRs) composed of the GABAB1 (GB1) and GABAB2 (GB2) subunits

Therefore, targeting ferroptosis emerges as a promising strategy for amyotrophic lateral sclerosis treatment

Hepatotoxicity has been uncommon (less than 1%) in rheumatoid arthritis patients

PMID: 41380101

For instance, Behnammanesh et al., proved that canagliflozin, but not empagliflozin or dapagliflozin, inhibits VSMCs proliferation and migration in pharmacologically relevant concentrations (Behnammanesh et al