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These tests included: (1) measuring the response to a 50 ms gap in the background sound (16 kHz pure tone, 70 dB SPL), presented 100 ms before a loud startle pulse (110 dB SPL, 50 ms duration)

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The movement of the mouse was tracked including the sequence of arm entries by EthoVision (Noldus Information Technology)

Sikiric, P., Skrtic, A., Gojkovic, S., Krezic, I., Zizek, H., Lovric, E., Sikiric, S., Knezevic, M., Strbe, S., Milavic, M., Kokot, A., Blagaic, A

Risk of Increased Intracranial Pressure Retinoids, often prescribed for acne or skin conditions, can increase the risk of a rare but serious side effect called intracranial hypertension (increased pressure in the brain) when combined with doxycycline