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They found that at the highest dosage of 4.8 mg survodutide weekly, study participants lost 14.9% of their body weight in comparison with a placebo group (2.8% weight loss) [122]

Consequently, oxidative stress occurs, and when it becomes excessive, it can lead to muscle damage

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10.3945/jn.114.202192 121 RomeoL.IoriR.RollinP.BramantiP.MazzonE

There are 497 human genes that encode a cofactor-dependent enzyme, of which at least 193 (39%) reportedly harbor disease-causing variants [69, 70] (Additional file 8 : Table S6)