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In terms of redox homeostasis, the SSP eliminates reactive oxygen species (ROS) through the production of glutathione (GSH) and nicotinamide adenine dinucleotide phosphate (NADPH), thereby preventing tumor cell apoptosis and mediating drug resistance

JHU083 JHU083 is a prodrug form of L-DON designed to be cleaved by tissue proteases and other enzymes in the cancer, thereby limiting its effects on other organs [87, 102] (Fig

Neutralization activity was pan-genotypic as tested with HDV enveloped with HBsAg of HBV genotypes A-H

Chronic ethanol consumption can lead to mitochondrial dysfunction, which increases mitochondrial permeability and causes the release of pro-apoptotic factors

Samioti, V., Kriti, E., Spanou, A., Tsironi, T., & Panagou, E