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All participants were confirmed to be experiencing a depressive episode using structured psychiatric interviews and rating scales like the HDRS-17 and MADRS

Takeshita S, Kaji K, Kudo A

The concept of the ROSImmune Mismatch is critical because it moves beyond the general observation of oxidative stress to define the specific, differential selection pressure that favors tumor survival and immunosuppressive cells over anti-tumor effector cells

It upregulates several crucial glycolytic enzymes, including LDHA, GLUT1, enolase 1 (ENO1), triosephosphate isomerase 1 (TPI1), PGK1, PKM2, and G6PD [62,63,64]