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J Cell Biol

If patients experience persistent difficulty with injections, inconsistent medication effects, or injection site reactions, they should contact their healthcare provider for additional guidance

Impaired heme production, leading to blood cells with less oxygen-carrying hemoglobin and, over time, microcytic anemia

These pathological features are accompanied by synaptic loss, chronic neuroinflammation, mitochondrial dysfunction, oxidative stress, and progressive neuronal degeneration (Wang et al., 2020