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Disclosures: Arunkumar Krishnan: Nothing to Disclose, Diptasree Mukherjee: Nothing to Disclose, Carolin Schneider: Nothing to Disclose, Tinsay Woreta: Nothing to Disclose, Saleh Alqahtani: Nothing to Disclose 1624 SAROGLITAZAR IS MORE EFFECTIVE THAN SIMVASTATIN IN REDUCING STEATOSIS IN PATIENTS WITH MET-ALD Anand Kulkarni 1 Ramyasri Ramagundam 2 Zaid Mohammed Gangdany 2 Mithun Sharma 3 Manasa Alla 2 Shantan Venishetty 2 Sowmya T R 2 Padaki Nagaraja Rao 2 Nageshwar Reddy 2 , 1 Asian Institute of Gastroenterology, 2 AIG Hospitals, 3 ASIAN INSTITUTE OF GASTROENTROLOGY PVT LTD Background: MetALD is the new term proposed to identify patients with steatotic liver disease, who concomitantly consume alcohol (210-420 g/week)

(121) published in 2024 revealed a novel mechanism by which AhR, as a uremic toxin receptor, promotes renal senescence and fibrosis: IS upregulates and activates AhR in renal tubular epithelial cells, and AhR can interact with peroxisome proliferator-activated receptor gamma coactivator 1-alpha (PGC1), promoting its ubiquitin-mediated degradation through its E3 ubiquitin ligase activity, thereby inhibiting mitochondrial biogenesis

Both aerobic and resistance exercise results in a significant increase in GH secretion, being its level correlated with exercise intensity [42, 43]

For those dealing with IBS or IBS-like symptoms, or gut-related inflammation in general, its easy to see why the BPC-157 gut health story has captured so much attention

Low MCH = hypochromia (cells carry less hemoglobin)