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Chromatin immunoprecipitation Control and TXNIP KO HepG2 cells were treated with 2 M JQ1 for 3 h, then were fixed with 1% formaldehyde for 10 min

Another mechanism through which Aos contribute to oxidative stress involves the activation of toll-like receptor 4 (TLR4) on microglia [87], the brains resident innate immune cells