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Taking into account the main hypothesis of the autoimmune origin of MS, in which the disease would be triggered by the infiltration of autoreactive T lymphocytes in the CNS, it is reasonable to consider that lymphocyte secreted factors contribute to astrocytes activation in MS

B-S C, Zeng Z, Mu H, Wang Z, McQueen T, Protopopova M, Cortes J, Marszalek J, S-B P, Davis RE, Thornton DE, Andreeff M , Konopleva M

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