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and their induced urolithin C dehydroxylase operon are primary contributors to UA biosynthesis (17)

Supplement wisely: Consider supplements like liposomal glutathione or methylated folate to enhance detoxification processes without overwhelming the system

Preclinical studies (in vitro and animal) reveal mechanistic benefits such as gut microbiota modulation, improved barrier function, and metabolic regulation

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Moreover, although resveratrol is generally well-tolerated at doses of up to 1 g/day, safety concerns regarding potential estrogenic stimulation in hormone-sensitive tissues remain a barrier to long-term studies in populations with hormone-sensitive conditions