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The most common causes include B12 supplementation (particularly injections), liver disease releasing stored B12, haematological disorders increasing B12-binding proteins, and chronic kidney disease reducing B12 excretion

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I typically use a B complex to support multiple areas of health, unless theres a clear need for high doses of one nutrient

So when were saying biotin causes acne because it affects B5 levels, how much biotin do you need to be consuming for it to affect B5