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At 30 min, 5 h, and 24 h of ligation time, there were marked dilatation and congestion of blood vessels in the portal tracts, central veins, and inusoids, along with the zones of confluent necrosis affecting liver lobuli and the portal tract, which occured at 24 h ligation time

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In these cases, IA therapy is generally restricted to selected patients with a high disease burden who remain symptomatic despite optimized standard therapy, including long-term macrolides