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Tryptophan-derived indoles act via the aryl hydrocarbon receptor (AhR) to concurrently enhance mucosal immunity and epithelial barrier integrity, which indirectly shapes ENS excitability and gut reflex coordination 62

10.1016/s0140-6736(76)91677-9 49 HamlinM

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In the following implementation, we applied our framework to exemplary cases from the cities of Xian and Luoyang, whose historic areas share similarities with Kaifeng, in order to compare the results and derive references that can directly inform detailed street renewal policies