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*Correspondence: Laila Abdullah, [email protected] This article was submitted to Alzheimers Disease and Related Dementias, a section of the journal Frontiers in Aging Neuroscience Disclaimer All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers

Recognising the cause of deficiency helps guide the appropriate form of treatmentwhether through supplements, dietary adjustments, or managing an underlying medical condition

Post-exercise metabolic changes, including elevated cortisol and altered blood flow patterns, may affect peptide distribution and receptor availability

Singh, M.D, DABFM, DABOM, system medical director of weight management and obesity medicine at Henry Ford Health

Cerebellar microglia may also experience metabolic stress, as observed in CSF1R-related leukoencephalopathy (CRL), a rare genetic disorder characterized by an autosomal dominant mutation in the CSF1R gene