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Mechanism 3: 5-alpha Reductase Inhibition Preliminary data suggests GHK-Cu may inhibit 5-alpha reductase, the enzyme that converts testosterone to DHT the primary driver of androgenetic alopecia

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Although our analyses showed no significant differences in baseline Glx/tNAA (or Glu/tNAA or Gln/tNAA) between the naltrexone and placebo groups measured 5 min before the ketamine infusion, suggesting that naltrexone does not independently affect glutamatergic measures at that early time point, our study was not designed with a dedicated placebo-infusion arm to assess its effects over the duration of the infusion