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Flavonoids are metabolized and bioavailability is enhanced by enzymes found in the liver, small intestine, and large intestine, as well as gut microbes in the small intestine and colon

Previous studies have indicated that intestinal iron overload, such as that induced by ferric citrate, damages epithelial villi and goblet cells, leading to reduced expression of tight junction proteins [21]

Cells were counted from randomly selected high-power fields (200) from each section under light microscopy, and the rates of TUNEL-positive cells were calculated

Found in nearly every cell, this antioxidant is central to detoxification, cellular repair, and immune balance. Yet, its bioavailability in traditional supplements is limited due to breakdown in the digestive tract

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