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To reduce the risk of gynecomastia, our patients take an AI (aromatase inhibitor) or a SERM (selective estrogen receptor modulator)

it's a philosophical one in study design

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Challenges include batch-to-batch variability, absence of standardized extraction protocols, and inconsistent concentrations of bioactive constituents, all of which complicate compliance with Good Manufacturing Practice (GMP) standards and hinder reproducibility in clinical trials