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We acknowledge the members of the Cell Imaging Core at the Turku Centre for Biotechnology and the Laboratory of Electron Microscopy at the University of Turku

H 2 O 2 at a concentration of 100 M was able to suppress GJIC by 50%

03 Performance evaluation and quantitative analysis The standard curves show excellent linearity and high sensitivity

3.3 Oxidative signals stimulate the diversity of smooth muscle cells in atherosclerosis With atherogenic risk factor stimuli, VSMCs can undergo phenotypic switching and subsequently migrate toward the intima, synthesize excess extracellular matrix, and release inflammatory cytokines by either redox signaling-mediated or redox signaling-independent mechanisms ( The atherogenic risk factor-impaired VSMC redox balance characterized by excessive ROS directly or indirectly affects VSMC phenotypic switching, proliferation, migration, and apoptosis, which play essential roles in mediating, integrating, and executing atherogenic signal transduction (San Martn and Griendling, 2010

The only accurate way is a six-hour urine provocative test