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The progressive damage of peripheral nerves is the main component of this disease and causes pain, sensory loss and changes of mechanosensitivity

ASK1, apoptosis-regulated signaling kinase 1

In a retrospective analysis aiming to identify the most frequent and reliable clinical and biochemical abnormalities that aid in determining when to start emergency treatment, the authors identified vomiting and metabolic acidosis with partial respiratory compensation and hyperammonemia as the most reliable (182)

Our findings extend and complement the study by Bechtold et al., who reported lower levels of free carnitine in FHT (Bechtold et al

This is a disease with a clear correlation to UV radiation