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Its primary models are cognitive paradigms and neuroprotection models (including stroke-related models in some research), and its investigated mechanism centers on BDNF expression and neurotrophic signaling

Clinical reality: Cerebrolysin used in some regions clinically

Recovery differs from patient to patient but typically can range from 6-12 weeks until total recovery from the point of treatment

Thus, these cells tend to be much less metabolically active, even in healthy states (Bibby et al., 2005)

A double-blind, randomized, placebo-controlled, pilot clinical trial examining buspirone as an adjunctive medication during buprenorphine-assisted supervised opioid withdrawal