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Radiotherapy directly damages the DNA of tumor cells through high-energy rays, leading to cell death

Annals of the New York Academy of Science 890, 167-172CrossRefGoogle ScholarPubMed 55Ferris, C.D., Jaffrey, S.R., Sawa, A

This mechanism is not fully elucidated and it is possible that it acts via the IGF-1 receptor (not GHR) in localized concentrations

These collective results demonstrate that TLYY administration promotes the repair of the intestinal barrier and ameliorates intestinal damage in DSS-induced colitis

Organoids, due to their capacity to replicate the original tumor characteristics and immune microenvironment, are recognized as powerful tools for studying cancer immunotherapy [197]