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Active ingredients of Chinese herbal medicine precisely target fatty acid metabolic pathways to exert anti-inflammatory, antioxidant and anti-apoptotic effects, restore mitochondrial function, and thereby alleviate RF

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Pharmacological inhibition of the NR4A2-SQLE axis has been shown to reduce immunosuppression and improve the efficacy of ICB therapies, highlighting its potential as a therapeutic target in glioblastoma ( Furthermore, cholesterol in glioblastoma is redistributed and enriched in the tumor microenvironment, especially in the form of HDL-type cholesterol, due to the metabolic co-dependence between tumor cells and their environment

Large-scale integration of meta-QTL and genome-wide association study identifies genomic regions and candidate genes for photosynthetic efficiency traits in bread wheat