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Irritable bowel syndrome pathophysiology studies draw attention to the importance of bacteria through fecal transplantation experiments from patients with IBS-C and IBS-D to germ-free (GF) animals

Due to ACE2 and DOPA decarboxylase co-express and co-regulate in non-neuronal cell types, the dopamine synthesis route may be implicated in the pathogenesis of COVID-19 [39, 40]