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doi: 10.2217/fmb-2021-0222 367 NeelakantanPSubbaraoCSharmaSSubbaraoCVGarcia-GodoyFGutmannJL

In addition, pro-inflammatory cytokines can act to steal tryptophan away from serotonin and melatonin pathways (via up-regulation of the enzymes IDO and TDO), increasing the activity of the NMDA agonist quinolinic acid, and further antagonising stimulation of NMDA pathways, which subsequently exacerbates mood and sleep issues

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PL: Funding acquisition, Methodology, Resources, Supervision, Validation, Writing review & editing, Conceptualization

Dietary patterns focused on reducing inflammatory response in vivo through the intake of anti-inflammatory and antioxidative foods are thought to hold the potential of ameliorating osteoporosis (130)