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Prostaglandin H2 is then converted to prostaglandin D2 by either hematopoietic or lipocalin type of prostaglandin D2 synthase

coli CARS showed that the lysine residues within the 73 KIIK 76 and 266 KMSK 269 motifs are important for CPERS activity (but not for aminoacylation activity) and likely serve as PLP binding sites ( In mammals, there are two isoforms of CARS: CARS1, which is localized in the cytosol, and CARS2, which is localized in the mitochondria ( in vivo and metabolomic analyses, has strengthened the view that CARS2 is the principal source of intracellular persulfides (Zainol et al., 2023)

Chem Biol Interact (2012) 195:2534

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It is a complex polygenic trait prevailing around two-thirds of the male population