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Kovacs MG, Kovacs ZZA, Varga Z, Szucs G, Freiwan M, Farkas K, et al

In vitro research frequently uses cultured cell models to assess vascular endothelial growth factor pathway activity and wound-closure rates

Accordingly, any factors that restrict the migration of these stem-like CD8 + T cells from TdLNs into tumor sites presumably constitute a critical barrier for resistance to cancer immunotherapy, including dysregulated chemokine signaling, vascular barriers, and physical stromal obstacles

This beneficial action was retained regardless of model type and reperfusion time

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