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In absolute terms, participants receiving tesofensine 0.5mg lost an average of 11.3kg over 24 weeks, while those on the 1.0mg dose lost an average of 12.8kg, compared to just 2.2kg in the placebo group

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C-Src is yet another pathway that control various biological functions where its aberrant regulation can lead to anchorage-independent growth, survival, tumor vascularity, migration, metastasis, survival and invasion [93]

Patients with a history of other substance use disorders are at higher risk for developing OUD