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Selectivity of commonly used pharmacological inhibitors for cystathionine beta synthase (CBS) and cystathionine gamma lyase (CSE)

In laboratory investigations, researchers found that NNMT overexpression correlates with obesity and metabolic dysfunction, while its inhibition produces remarkable metabolic benefits

In fact, an animal model published in The Journal of Nutritional Biochemistry showed that treating mice with okra extract not only helped lower cholesterol levels, but also decreased both blood sugar and triglycerides as well

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This would imply that copper binding is common in disordered proteins