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AR alterations inform circulating tumor DNA detection in metastatic castration resistant prostate cancer patients

[23] The binding of an androgen to the androgen receptor results in a conformational change in the receptor that, in turn, causes dissociation of heat shock proteins, transport from the cytosol into the cell nucleus, and dimerization

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37 These controls included 42 healthy children ranged from 27 years of age with no history of developmental delay or neurological symptoms