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[11] Use is not recommended in those who are allergic to cobalt or have Leber's disease

doi: 10.2337/db18-0696 87 BadmanMKPissiosPKennedyARKoukosGFlierJSMaratos-FlierE

According to Roch et al

The limited impact of AKT inhibition on GSK3 phosphorylation suggested that this interaction is unlikely to represent the dominant mechanism by which Ssu72 regulates GSK3 activity