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(Those chronic diseases are heart disease, cancer, Alzheimers and related neurodegenerative diseases and Type 2 diabetes and related metabolic dysfunction.) Medicine 3.0, though, aims to proactively prevent those things for as long as possible and allow us to maintain better health deeper into old age

Alpha lipoic acid (50mg) is a naturally occurring antioxidant compound involved in energy metabolism

Here, we found that Pit-1 overexpression or knockdown in human breast cancer cell lines induced profound phenotypic changes in the expression of proteins involved in cell proliferation, apoptosis, and invasion

doi:10.4088/JCP.v67n0905 PubMed 53

This process regulates the miR-770-3p/triggering receptor expressed on myeloid cells 2 (TREM2) axis, thereby promoting microglial transition from the pro-inflammatory M1 to the anti-inflammatory M2 phenotype, which alleviates cognitive impairment and neuronal damage in AD mouse models [191]