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In conjunction with SAR attributes, the pharmacokinetics, biotransformation, and metabolism of flavonoids play a significant role in determining their pharmacological effects

A systematic review of randomized controlled trials (RCTs) pinpointed the generally subpar methodological quality in the prevailing research on this topic [4]

Histone methylation in atherosclerosis and vascular intimal hyperplasia Atherosclerosis, one of the primary causes of cardiovascular death worldwide, is initiated by endothelial dysfunction and lipid accumulation [5, 48], and it is characterized by fibrotic cell proliferation, chronic inflammation, lipid accumulation, and immune disorder in the vessel wall [49]