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Since mouse microbiome profiles often highly correlate with body weight and fat composition, this study was designed to test whether the cecal microbiomes of DIO mice treated with NNMTi and LD were comparable to the microbiomes of age-matched lean counterparts and distinct from microbiomes of DIO mice maintained on a high-fat Western diet (WD) or subjected to LD switch alone

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(1999) showed CRH-deficient mice can have normal stress-induced suppression of food intake, implicating other CRH-like molecules

A health intake form is completed before each session to confirm appropriateness for the individual client