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The direct interaction between MAPKAPK2 and Nrf2 remains to be confirmed through luciferase reporter or co-immunoprecipitation assays, and the association between MAPKAPK2 expression and promoter methylation should be validated using bisulfite sequencing or methylation array analyses

Yes, you can take them together, as they work through different mechanisms

When nutrients are abundant (i.e., when youre eating regularly), mTOR reduces autophagy because the cells have plenty of fuel

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Stained whole nerves were imaged using ZEISS Axio Observer 7 equipped with an Apotome.2 (Carl Zeiss Microscopy GmbH, Jena, Germany)