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In a cervical cancer cell line (HeLa), the compound reduced cell proliferation in a concentration- and time-dependent way and lowered expression of phospho-Akt and SIRT1, two proteins tied to tumor progression, while a non-cancer reference cell line was less affected

Most researchers report initial changes between two and three months, with more substantial improvements visible at four to six months

10.3109/17453679808999268 35 FortinC

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