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The seven additional Phase 3 readouts expected this year will provide the larger safety database the FDA needs to make this determination

Keene, W

In vitro, manipulating cellular ROS has been found to slow fibroblast wound migration [115, 116] and to prevent the formation of postoperative adhesions in surgical animal models [112]

(112) confirmed that gut microbiota-derived phenyl sulfate is an important contributor to albuminuria in diabetic kidney disease, suggesting that uremic toxin production and absorption can be reduced through modulation of gut microbiota metabolism