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Understanding the complexity of the matrix metalloproteinase system and its relevance to age-related diseases: Age-related macular degeneration and Alzheimers disease

These effects stem from upregulated enzyme activity including 3-HSD and 17-HSD, which drive testosterone biosynthesis [9]

the metabolically stabilized 6-AH family member, D-Nle-Tyr-Ile-NH(CH 2 ) 5 CONH 2 had a t 1/2 in blood of 80 min compared to the parent compound Norleual (Nle-Tyr-Leu- -(CH 2 NH 2 ) 3-4 -His-Pro-Phe, SEQ ID NO: 1), which had a t 1/2 in blood of 5 min