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Similar to the mechanism underlying coronary calcification, lipid deposition, inflammatory cell infiltration, extracellular matrix dysregulation, and the osteogenic transformation of valvular interstitial cells contribute to the pathophysiology of this disease [74]

(3) Johansen PB, Nowak J, Skjaerbaek C, Flyvbjerg A, Andreassen TT, Wilken M, Orskov H

Jumping to the full dose immediately would produce severe nausea and vomiting in most people

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