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Increased relative lung and heart weights as well as growth retardation were reported after exposure to 8200 mg/m 3 , though there were no increases in mortality in any of the exposed groups (Kruysse et al., 1975)

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Retatrutide additionally shows a dose-dependent increase in heart rate, attributed to its glucagon-receptor activity, and indirect network meta-analyses flag the highest adverse-event burden among the modern agents for the most potent drugs

Kazim SF, Sharma A, Saroja SR, Seo JH, Larson CS, Ramakrishnan A, Wang M, Blitzer RD, Shen L, Pea CJ, et al