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Intrahepatic gene expression profiles and alpha-smooth muscle actin patterns in hepatitis C virus induced fibrosis

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As critically reviewed by others [63,64,65,66,67], antisense oligonucleotides (ASOs) and small interfering RNA (siRNA) therapies work by inhibiting the mRNA transcripts of a selected protein, halting its translation and resulting in the protein mRNAs degradation [63,64,65,66,67]

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