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Y.et al (2016)

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MR-Egger intercept can detect horizontal pleiotropy through its intercept test and provide a corrected estimate of pleiotropy ( 2.4.3 MVMR analysis Multivariate Mendelian randomization (MVMR) analysis was conducted to examine the potential impact of confounding factors, such as smoking, MDD, mood swings, alcohol use, and T2DM, on the association between diet-related antioxidant exposure factors and vitiligo ( 2 3 Results Twelve dietary antioxidants were analyzed to determine their potential causality with vitiligo

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Notably, the immune system influences bone metabolism primarily through the innate and adaptive response