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284 , E671E678 (2003)

Dexamethasone, in particular, has been linked to metabolic disturbances such as hyperglycemia, insulin resistance, hepatic steatosis, and the development of type II diabetes ( Given the toxicity associated with prolonged glucocorticoid use, there is a growing interest in exploring dietary and botanical interventions to mitigate these adverse effects

On the other hand, the pancreatic sections from diabetic group showed interstitial edema, shrinkage of the acini, loss of cells in islands of Langerhans, vacuolated -cells, congestion, and hemorrhage (Fig