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For example, alginate possesses a large number of carboxyl groups in its polymer framework, which are converted into negatively charged carboxylate ions in alkaline conditions, leading to pH-responsive expansion that accelerates drug release [345]

[DOI] [PubMed] [Google Scholar] 63.Curiel T.J., Wei S., Dong H., Alvarez X., Cheng P., Mottram P., Krzysiek R., Knutson K.L., Daniel B., Zimmermann M.C., et al

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