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10.1177/1934578x0600100210 [DOI] [Google Scholar] Deng R, Chen Y, Deng X, Huang Z, Zhou S, Ren B, Jin G, & Hursthouse A (2021)

This latter finding is of particular interest, as rather than simply modifying the PDHc, glutarate formed a fatty acid conjugate that binds to the lipoylated catalytic arm of PDHc

This article aims to provide a comprehensive overview of the role of Gln transporters in DSMTs, along with an exploration of targeted therapeutic drugs, with the goal of providing valuable insights into the drug discovery process for DSMTs therapy and deepening our understanding of the underlying mechanisms

They are considered unsafe and even ineffective