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Current clinical strategies for the management of PDN include glycolic control and treatment with drugs such as tricyclic compounds, serotonin noradrenalin reuptake inhibitors, -lipoic acid, anticonvulsants, opiates, membrane stabilizers and topical capsaicin

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After 2 min, 0.1 ml samples were diluted to a final volume of 1 ml containing 1 mM GSH, 1 mM CDNB in 0.1 M potassium phosphate buffer, pH 6.5, according to the standard procedure of Habig et al