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Piccini JP, Caso V, Connolly SJ et al (2022) Safety of the oral factor XIa inhibitor asundexian compared with apixaban in patients with atrial fibrillation (PACIFIC-AF): a multicentre, randomised, double-blind, double-dummy, dose-finding phase 2 study

D., Goldfield, G

Complement RegulatorAcquiring Surface Protein 1 of Borrelia burgdorferi Binds to Human Bone Morphogenic Protein 2, Several Extracellular Matrix Proteins, and Plasminogen

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In another study, HTY demonstrated hippocampal neurogenesis when administered orally and it activated neurogenesis in the dentate gyrus of normal adult mice, aged wild-type mice, and Btg1-knockout mice modeling accelerated neural aging, HTY-induced neuroprotection involved reduction of oxidative stress markers and apoptotic neuronal death, suppression of microglial activation and pro-inflammatory cytokine release, and functional integration of newly generated neurons into hippocampal memory circuits