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TREM2 interacts with TDP-43 and mediates microglial neuroprotection against TDP-43-related neurodegeneration

The VEGF/VEGFR2 pathway enhances the tip cell phenotype by increasing the activity of 6-phosphofructose-2-kinase-fructose-2,6-bisphosphatase (PFKFB3), which produces fructose-2,6-bisphosphate, a positive allosteric effector of glycolysis

doi: 10.1172/JCI25112 233 PasseriniLBacchettaR

Mangiferin markedly increases the activities of the tricarboxylic acid cycle and antioxidant defense enzymes in MI (78)